A | B | C | D | E | F | G | H | CH | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | 0 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9
Names | |
---|---|
IUPAC name
1-(Dimethylamino)ethylphenyl N-methylcarbamate
| |
Identifiers | |
3D model (JSmol)
|
|
ChemSpider | |
KEGG | |
PubChem CID
|
|
UNII | |
CompTox Dashboard (EPA)
|
|
| |
| |
Properties | |
C12H18N2O2 | |
Molar mass | 222.288 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C 77 °F, 100 kPa).
|
Miotine is an anticholinesterase drug. Miotine was the first synthetic carbamate that was used clinically.[1]
Unlike the miotine analog neostigmine, it doesn't have a quaternary ammonium group to give it a permanent positive charge. It can exist as an uncharged free base which could allow it to cross the blood–brain barrier and cause unwanted central nervous system (CNS) side effects.[2]
See alsoedit
Referencesedit
- ^ "Archived copy" (PDF). Archived from the original (PDF) on 2009-05-09. Retrieved 2008-01-04.
{{cite web}}
: CS1 maint: archived copy as title (link) - ^ "An introduction to drugs,their action and discovery" (PDF).
>Text je dostupný pod licencí Creative Commons Uveďte autora – Zachovejte licenci, případně za dalších podmínek. Podrobnosti naleznete na stránce Podmínky užití.
Text je dostupný za podmienok Creative
Commons Attribution/Share-Alike License 3.0 Unported; prípadne za ďalších
podmienok.
Podrobnejšie informácie nájdete na stránke Podmienky
použitia.