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Selenophos
| |
| Names | |
|---|---|
| Preferred IUPAC name
Se- O-ethyl ethylphosphonoselenoate | |
| Other names
Seleno-VE[2]
| |
| Identifiers | |
3D model (JSmol)
|
|
| ChemSpider | |
PubChem CID
|
|
CompTox Dashboard (EPA)
|
|
| |
| |
| Properties | |
| C10H24NO2PSe | |
| Molar mass | 300.252 g·mol−1 |
| Hazards | |
| Lethal dose or concentration (LD, LC): | |
LD50 (median dose)
|
21 μg/kg (mouse, subcutaneous) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa).
| |
Selenophos is an extremely potent organophosphate acetylcholinesterase inhibitor.[3] It is the selenium analog of the VE nerve agent.
See also
References
- ^ Nachmansohn, David (1 July 1969). "Proteins of Excitable Membranes". The Journal of General Physiology. 54 (1): 187–224. doi:10.1085/jgp.54.1.187. PMC 2225914. PMID 19873642.
- ^ Mager, Peter P. (1984). Multidimensional pharmacochemistry : design of safer drugs. Orlando: Academic Press. p. 354. ISBN 978-0-12-465020-6.
- ^ Akerfeldt, Stig.; Fagerlind, Lars. (January 1967). "Selenophosphorus Compounds as Powerful Cholinesterase Inhibitors". Journal of Medicinal Chemistry. 10 (1): 115–116. doi:10.1021/jm00313a032. PMID 6031689.
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