TL-301 - Wiki slovník

TL-301
Identifiers
CAS Number	619-34-1;
3D model (JSmol)	Interactive image;
ChemSpider	30001;
PubChem CID	32369;
CompTox Dashboard (EPA)	DTXSID60210926 ;
	InChI InChI=1S/C7H15Cl2N/c1-7(2)10(5-3-8)6-4-9/h7H,3-6H2,1-2H3 Key: WAEDMQMDOHQPFL-UHFFFAOYSA-N;
	SMILES CC(C)N(CCCl)CCCl;
Properties
Melting point	13.7 °C (56.7 °F; 286.8 K)
Boiling point	67–68 °C (153–154 °F; 340–341 K)
Hazards
	Lethal dose or concentration (LD, LC):
LD50 (median dose)	1.1 mg/kg (subcutaneous, mice)(hydrochloride salt); 1 mg/kg (subcutaneous, rats)(hydrochloride salt); 0.5 mg/kg (intravenous, rat)(hydrochloride salt); 22 mg/kg (oral, mice)(hydrochloride salt); 0.5 mg/kg (subcutaneous, mice)(hydrochloride salt); 2 mg/kg (subcutaneous, rats)(hydrochloride salt)
LDLo (lowest published)	25 mg/kg (oral, rats)(hydrochloride salt)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Infobox references

TL-301 is a nitrogen mustard vesicant.^[1]^[2]^[3]

References

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Zdroj:https://en.wikipedia.org?pojem=TL-301
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v t e Nitrogen mustards
Vesicants	HN1 HN2 HN3 TL-301 TL-481 TL-512 TL-513 TL-695 TL-995
Antineoplastic agents	Aniline mustard Bendamustine Chlorambucil Cyclophosphamide Mannomustine Melphalan Mustamine Phenylenediamine mustard Quinacrine mustard Spiromustine
Neurotoxins	Acetylcholine mustard Acetylethylcholine mustard Benzilylcholine mustard Choline mustard Decamethonium mustard DMEA DSP-4 Ethylcholine mustard Hemicholinium mustard Propylbenzilylcholine mustard
Other	Dibenamine Phenoxybenzamine SY-28

Identifiers

CAS Number	619-34-1
3D model (JSmol)	Interactive image
ChemSpider	30001
PubChem CID	32369
CompTox Dashboard (EPA)	DTXSID60210926
InChI InChI=1S/C7H15Cl2N/c1-7(2)10(5-3-8)6-4-9/h7H,3-6H2,1-2H3 Key: WAEDMQMDOHQPFL-UHFFFAOYSA-N
SMILES CC(C)N(CCCl)CCCl
Properties
Melting point	13.7^[1] °C (56.7 °F; 286.8 K)
Boiling point	67–68^[1] °C (153–154 °F; 340–341 K)
Hazards
Lethal dose or concentration (LD, LC):
LD₅₀ (median dose)	1.1 mg/kg (subcutaneous, mice)(hydrochloride salt)^[2] 1 mg/kg (subcutaneous, rats)(hydrochloride salt)^[2] 0.5 mg/kg (intravenous, rat)(hydrochloride salt)^[2] 22 mg/kg (oral, mice)(hydrochloride salt)^[2] 0.5 mg/kg (subcutaneous, mice)(hydrochloride salt)^[3] 2 mg/kg (subcutaneous, rats)(hydrochloride salt)^[3]
LD_Lo (lowest published)	25 mg/kg (oral, rats)(hydrochloride salt)^[4]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Infobox references